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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TP53BP1 All Species: 15.76
Human Site: T434 Identified Species: 57.78
UniProt: Q12888 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12888 NP_001135451.1 1972 213574 T434 T V S P Q A S T P I S Q S T P
Chimpanzee Pan troglodytes XP_001158270 1972 213535 T434 T V S P Q A S T P I S Q S T P
Rhesus Macaque Macaca mulatta XP_001107220 1972 213653 T434 T V S P Q A S T P I S Q S T P
Dog Lupus familis XP_849774 1976 214088 T439 V I S P Q A S T P V S Q S T P
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001082071 2104 231430 S482 E L S T S E P S E V T D T D Y
Zebra Danio Brachydanio rerio NP_001073639 1709 184731 S234 E E D V L V S S Q D D M F E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798355 2169 238737 P454 T K E Q P E E P R T T G Q A M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 89.2 N.A. N.A. N.A. N.A. N.A. N.A. 36.9 34.4 N.A. N.A. N.A. N.A. 20.5
Protein Similarity: 100 99.5 98.2 93.6 N.A. N.A. N.A. N.A. N.A. N.A. 54.5 51.3 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 100 100 80 N.A. N.A. N.A. N.A. N.A. N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 40 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 58 0 0 0 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 0 0 0 0 0 0 15 15 15 0 15 0 % D
% Glu: 29 15 15 0 0 29 15 0 15 0 0 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 43 0 0 0 0 0 % I
% Lys: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 15 % K
% Leu: 0 15 0 0 15 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 15 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 58 15 0 15 15 58 0 0 0 0 0 58 % P
% Gln: 0 0 0 15 58 0 0 0 15 0 0 58 15 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % R
% Ser: 0 0 72 0 15 0 72 29 0 0 58 0 58 0 0 % S
% Thr: 58 0 0 15 0 0 0 58 0 15 29 0 15 58 0 % T
% Val: 15 43 0 15 0 15 0 0 0 29 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _